Poster presentations II

SESSION I: Neurodevelopment / Regeneration

P.084 | Maria-del-Mar Romero-Alemán (Universidad de Las Palmas de Gran Canaria, Spain)
Hybrid nanofibers of aloe vera and honey are scaffolds for the guidance of dorsal root ganglion neurites and for the skin regeneration in murine models
P.085 | João M. M. Rocha (CNC, Universidade de Coimbra)
Cortical neuronal migration entails A2A receptor-driven neuronal polarization and axon formation
P.086 | Joana M. Marques (CNC, Universidade de Coimbra)
Adenosine A2A receptor contributes to hippocampal mossy fiber sprouting during epileptogenesis
P.087 | Ana Rita Brás (Faculdade de Farmácia, Universidade de Lisboa)
Cafeteria-diet effects on cognitive functions, anxiety and expression of parvalbumin and calretinin calcium-binding proteins in the juvenile rat
P.088 | João B. Moreira (iMM, Faculdade de Medicina, Universidade de Lisboa)
Modulation of subventricular zone neurogenesis by cannabinoid type 2 receptor and “exercise-regulated” neurotrophic factors
P.089 | Filipe A. Monteiro (Faculdade de Medicina, Universidade do Porto)
TLX3 specification of excitatory dorsal horn neurons involves repression of alternative inhibitory differentiation program
P.090 | Cláudia R. Marques (ICVS, Universidade do Minho)
A neuroprotective role played by secretome from mesenchymal stem cells against the action of alpha-synuclein on a caenorhabditis elegans model of Parkinson’s disease
P.091 | Helena Vilaça-Faria (ICVS, Universidade do Minho)
Mesenchymal stem cells secretome-derived exosomes: biological nanovesicles for the treatment of Parkinson’s disease?
P.092 | Andreia G. Pinho (ICVS, 3B's, Universidade do Minho)
Immunomodulatory and regenerative effect of adipose stem cell exosomes on spinal cord injury context
P.093 | Abeer Heskol (Instituto Gulbenkian da Ciência)
Investigating the importance of mitotic bookmarking by RBPJ/Notch signaling in vertebrate neurogenesis
P.094 | Rafael M. Miranda (i3S, Faculdade de Medicina, Universidade do Porto)
Unveiling the function of neph1 in the dorsal root ganglion–spinal circuit
P.095 | Marília Torrado (i3S, Faculdade de Medicina, Universidade do Porto)
Biodegradable dendrimers as novel tools to deliver neuroprotective nucleic acids in stroke
P.096 | Sofia Duque Santos (i3S, Faculdade de Medicina, Universidade do Porto)
The transport of therapeutic molecules to the ischemic brain: dendrimers as carriers in pre-clinical studies
P.097 | Fábio F. F. Garrudo (IST, Universidade de Lisboa)
P.098 | Federico Herrera (ITQB, Universidade NOVA de Lisboa)
Dinuclear zinc complexes as specific inhibitors of STAT3 phosphorylation at tyrosine 705

SESSION II: Cellular and Molecular Neurosciences

P.099 | Lucianna Lopes Do Couto (Faculdade de Medicina, Universidade de Lisboa)
Biochemical description, antiepileptic activity and pharmacological effects of PPNP7 (neuropolybin), a neuropeptide obtained from wasp venom
P.100 | Raphael Fabricio De Souza (Universidade Federal de Recife, Brasil)
Effect of exhaustive ultra-endurance vs moderate exercise on rodent cerebellum antioxidant capacity
P.101 | Raquel Alonso (Faculdade de Medicina, Universidade do Porto)
SPRR1A expression in experimental osteoarthritis. Is there a role in pain?
P.102 | Andreia Neves Carvalho (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Activation of the unfolded protein response in Parkinson's disease
P.103 | Sara R. Oliveira (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Circulating mirnas and implications in Parkinson's disease patients
P.104 | José D. Carvalho-Rosa (BioISI, Faculdade de Ciências, Universidade de Lisboa)
Endogenous VIP VPAC1 receptor activation during ictal and interictal-like activity induced in vitro by biccuculine and 0-Mg2+ modulates subsequent LTP expression in the rat hippocampus
P.105 | Vanda C. Nogueira (iMM, Faculdade de Medicina, Universidade de Lisboa)
Role of adenosine on the resistance to an anti-tumor agent in glioblastoma cell lines
P.106 | Margarida Beatriz (CNC, Universidade de Coimbra)
Correction of mutant huntingtin gene ameliorates mitochondrial function in pluripotent and neural stem cells derived from Huntington’s disease patients
P.107 | Maria João Nunes (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Targeting cholesterol metabolism in neuroblastoma by acting on HDACS
P.108 | Andreia Monteiro Silva (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Asyn familial mutations role on asyn fate and lysosomal dysfunction in a yeast model of Parkinson’s disease
P.109 | Luís Sousa (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Elucidating the role of synucleins in retinal neurodegeneration in Parkinson’s’ disease, diabetes and ageing
P.110 | Rita Perfeito (CNC, Universidade de Coimbra)
Intersection of exosome secretion and autophagy on alpha-synuclein spreading profile in Parkinson’s disease cell models
P.111 | Catarina Almeida (CICS, Universidade da Beira Interior)
CTBPS: novel transcriptional regulators of neurogenesis
P.112 | Rita Soares (iMM, Faculdade de Medicina, Universidade de Lisboa)
Mitochondrial dynamics: a target for neural stem cell fate regulation
P.113 | Ana Cristina Rego (CNC, Universidade de Coimbra)
C-SRC regulates NRF2 activity through PKCδ after oxidant stimulus
P.114 | Joana Paes de Faria (i3S,Universidade do Porto)
Pinch proteins regulate myelination of axons in the central nervous system

SESSION III: Sensory Processing

P.115 | Jorge Cardoso (iMM, Faculdade de Medicina, Universidade de Lisboa)
Principles of multisensory dynamics recorded in OC2M
P.116 | Anna F. Hobbiss (Fundação Champalimaud)
Somatic contributions to a defensive behaviour in Drosophila melanogaster
P.117 | Mirjam Heinemans (Fundação Champalimaud)
Learning about looming: does looming drive learning in rats?
P.118 | Marco R. Guimarães (ICVS, 3B's, Universidade do Minho)
Inflammatory profile influences chronic pain development after peripheral nerve injury
P.119 | Ana Margarida Cunha (ICVS, 3B's, Universidade do Minho)
Trait and state impulsivity in chronic pain: a rodent study
P.120 | Joana Mendes (ICVS, 3B's, Universidade do Minho)
Chronic pain effects on social behaviors in rats
P.121 | Ana R. Costa (CICS, Universidade da Beira Interior)
Bitter taste receptors are expressed in glioblastoma cell lines
P.122 | Aristela de Freitas Zanona (Universidade Federal de Recife, Brasil)
Effects of transcranial magnetic stimulation associated to sensory therapy on motor function of patients after stroke

SESSION IV: Rare Disorders

P.123 | Ricardo Moreira (CNC, Universidade de Coimbra)
Investigation of mutant ataxin-3 spreading in Machado-Joseph disease
P.124 | Catarina Oliveira Miranda (CNC, IBILI, Universidade de Coimbra)
Sustainable phenotypic ameliorations in Machado-Joseph disease/spinocerebellar ataxia type-3 can be reached by repeated systemic administrations of mesenchymal stromal cells – and can be monitored through proton magnetic resonance spectroscopy biomarkers
P.125 | Adriana Marcelo (Universidade do Algarve)
RNA-binding proteins: new molecular targets for polyglutamine diseases?
P.126 | Carlos A. Matos (CBMR, Universidade do Algarve)
CRISPR-CAS9 as a tool for silencing and correcting ATXN3, the gene causing machado-joseph disease
P.127 | Francisco Melo Mouro (iMM, Faculdade de MEdicina, Universidade de Lisboa)
Molecular evaluation of the endocannabinoid system in RTT mice-model: implications for cannabinoid-based treatments

SESSION V: Neural Circuits

P.128 | Carla Henriques (Instituto Gulbenkian de Ciência)
Genetic architecture for social learning in drosophila melanogaster
P.129 | Bárbara Coimbra (ICVS, Universidade do Minho)
Laterodorsal tegmentum projections to nucleus accumbens drive preference and increase motivation
P.130 | Carina Soares-Cunha (ICVS, Universidade do Minho)
Modulation of reward behaviors by nucleus accumbens indirect pathway
P.131 | Inês Guerra Mollet (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Neuronal signalling in the diabetic gut - evidence of enteric neuro-endocrine gabaergic regulation by subtype-specific KCTD auxiliary subunits
P.132 | Josephine Heine (Charité - Universitätsmedizin Berlin, Germany)
Transdiagnostic hippocampal shape analysis reveals shared hippocampal damage pattern in neuroimmunological disorders
P.133 | Joana Faria (i3S, Universidade do Porto)
Abnormal prefrontal-hippocampal connectivity supports pain-related working memory deficits
P.134 | Inês Marques-Morgado (iMM, Faculdade de Medicina, Universidade de Lisboa)
Impact of circadian shifting on functional brain connectivity
P.135 | Bárbara Pinto Correia (iMM, Faculdade de Medicina, Universidade de Lisboa)
How our brain solves dilemmas
P.136 | Natalia Madeira (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Temporal gating of synaptic competition in the lateral amygdala by cannabinoid receptor modulation of the thalamic input
P.136.05 | Ashley Novais (International Iberian Nanotechnology Laboratory, Braga)
High-density recording using a new concept of silicon neural probes

SESSION VI: Glia / Neuroinflammation

P.137 | Joana R. Guedes (CNC, Universidade de Coimbra)
IL-4 skews the microglial developmental program during cerebellar maturation
P.138 | Andreia Barateiro (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
S100B has a crucial role in inflammation and immune response in the in vivo model of multiple sclerosis
P.139 | Joana Moura Mateus (iMM, Faculdade de Medicina, Universidade de Lisboa)
From neural stem cells to oligodendrocytes: postnatal oligodendrogenesis as a target for MS therapy
P.140 | Marta Alonso Gomes (iMM, Faculdade de Medicina, Universidade de Lisboa)
Putative role of adenosine A2A receptors in promoting remyelination through adult oligodendrogenesis in the EAE model
P.141 | Daniela M. Magalhães (iMM, Faculdade de Medicina, Universidade de Lisboa)
Immunomodulatory effects of FTY720 in the depressive and anxiety-like behaviour in a mice model of social isolation
P.142 | Carla P. Fonseca (CICS, Universidade da Beira Interior)
Modulation of microglial reactivity by the anti-aging protein klotho
P.143 | Joana F. Silva-Rodrigues (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Peripheral axonal ensheatment is regulated by RAL GTPase and the exocyst complex
P.144 | Beatriz Cardoso (ITQB, Universidade NOVA de Lisboa)
Asymmetric post-translational modifications regulate the intracellular distribution of unstimulated STAT3 dimers
P.145 | Daniela Madeira (CNC, Universidade de Coimbra)
Alterations in connexin 43 triggered by amyloid-β in astrocytes: modulation by adenosine A2A receptors
P.146 | Inês Ribeiro (Universidade do Porto)
Methamphetamine and neuroinflammation: unveiling the crosstalk between glial cells and neurons
P.147 | Teresa Canedo (i3S, Universidade do Porto)
Microglia-astrocytes interaction in neuroinflammation under methamphetamine exposure
P.148 | Cátia Lopes (CNC, Universidade de Coimbra)
Astroglia control synaptic plasticity in an animal model of Alzheimer's disease
P.149 | Liliana Dias (CNC, Universidade de Coimbra)
Amyloid-β peptides affect astrocytic Ca2+ dynamics and exocytotic gliotransmitter release
P.150 | Beatriz Martins (iCBR, IBILI, Universidade de Coimbra)
Unraveling the effect of methylmercury exposure in neuroinflamamation
P.151 | Carolina Pina (iMM, Faculdade de MEdicina, Universidade de Lisboa)
Dysfunctional astrocytic GABA transporter in childhood absence epilepsy
P.152 | Sara Costa Silva (INEB, Universidade do Porto)
Assessing functional activity of astrocytes by calcium imaging: astrocytic calcium signals and the electrophysiological microenvironment

SESSION VII: Psychiatric Disorders / Addiction

P.153 | Miguel F. Ferreira (iMM, Faculdade de Medicina, Universidade de Lisboa)
“Over the moon” or “down in the dumps”? Contradictory effects of chronic adolescent exposure to HU-210 on depressive-like behavior
P.154 | Rita Gaspar (iCBR, Universidade de Coimbra)
Dynamic changes in microglia morphology and higher resilience to stress-induced anxious-behavior in a model of prenatal exposure to glucocorticoids
P.155 | Sofia Rodrigues (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Impact of acute stress in amygdala synaptic plasticity
P.156 | Joana G. Ribeiro (iMM, Faculdade de Medicina, Universidade de Lisboa)
Study of midbrain-hippocampal connectivity underlying drug-related memory formation
P.157 | Bruno Faustino (Faculdade de Psicologia, Universidade de Lisboa)
An experimental study of psychophysiological and behavioural indicators of nonconscious emotional reactions in a clinical sample
P.158 | João Valente Duarte (Universidade de Coimbra)
Investigating whole-brain MRI markers in neuropsychiatric disorders – separating disease duration from medication effects in schizophrenia and bipolar disorder

SESSION VIII: Neurodegeneration / Physiological Aging Brain

P.159 | Neide Vieira (ICVS, Universidade do Minho)
Sorting out sorting nexins role in cognition, and the modulator effect of stress
P.160 | Joana E. Coelho (iMM, Faculdade de Medicina, Universidade de Lisboa)
Neuronal adenosine A2A receptor overexpression promotes changes in glial phenotype in the hippocampus
P.161 | Diana Lobo (CNC, Universidade de Coimbra)
Blood-brain barrier dysfunction as a neuropathological feature in Machado-Joseph disease: results from human and MJD mouse samples
P.162 | David V. C. Brito (IZN, University of Heidelberg, Germany)
Bidirectional dysfunction in GADD45γ expression during mammalian aging impairs cognition and disrupts activity-dependent gene expression
P.163 | Nádia Rei (iMM, Faculdade de Medicina, Universidade de Lisboa)
Characterization of synaptic plasticity in non-motor synapses of the SOD1G93A ALS mouse model
P.164 | Tatiana Burrinha (CEDOC, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa)
Lysosome (dys)function with neuronal aging
P.165 | Joana R. Saraiva (iMM, Faculdade de Medicina, Universidade de Lisboa)
Modulation of NMDA receptor function by amyloid precursor protein
P.166 | Helena C. Brigas (iMM, Faculdade de Medicina, Universidade de Lisboa)
Elucidating the impact of γδ T cells on cognition
P.167 | Flavio Barbosa (Universidade Federal de Paraíba, Brasil)
Load effect on what-where-when memory in younger and older adults
P.168 | André Conceição (Universidade de Coimbra)
Transcriptional repression of mutant human ATNX3 using CRISPR interference mitigates the pathological phenotype of an in vivo Machado-Joseph disease model
P.169 | Ana Catarina Rodrigues-Neves (iCBR, Faculdade de Medicina, Universidade de Coimbra)
Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease?
P.170 | Carla S. Lopes (i3S, IBMC, Universidade do Porto)
Cdc25: a novel tau phosphatase and its impact on disease