Poster presentations I

SESSION I: Neurodevelopment / Regeneration

P.001 | Marta Esteves (CICS, Universidade da Beira Interior)
MicroRNA-124-enriched exosomes improve adult neurogenesis in the subventricular zone
P.002 | Filipa F. Ribeiro (iMM, Faculdade de Medicina, Universidade de Lisboa)
Postnatal hippocampal neurogenesis: adenosine A2A receptors as regulators of new neurons formation in the dentate gyrus
P.003 | João Martins (CIBIT-ICNAS, Universidade de Coimbra)
Neural basis for adult cognitive deficits in neurofibromatosis type 1 animal model: relevance for autism spectrum disorders
P.004 | Carla Cavaleiro (ICNAS, Universidade de Coimbra)
Impact of neurofibromatosis type 1 on early postnatal development: a behavioral approach
P.005 | Diana Chapela (Technophage S.A., iMM)
A zebrafish-based phenotypic screen to propel the discovery of new therapeutics for spinal cord injury
P.006 | Rui S. Rodrigues (iMM, Faculdade de Medicina, Universidade de Lisboa)
Cannabinoids and BDNF: modulators of postnatal neurogenesis
P.007 | Carmén M. Vieira (i3S, Faculdade de Medicina, Universidade do Porto)
Dissecting the molecular causes of NDE1-associated microcephaly
P.008 | Ricardo J. Rodrigues (CNC, Universidade de Coimbra)
P2 receptors control the migration of medial ganglionic eminence-derived interneurons
P.009 | José C. Mateus (i3S, Faculdade de Medicina, Universidade do Porto)
A new 3D-structured microelectrode array for enhanced in vitro electrophysiology
P.010 | Diogo M. Lourenço (iMM, Faculdade de Medicina, Universidade de Lisboa)
The effect of the non-psychoactive cannabinoid cannabidivarin and TRPV1 agonist capsaicin on neural stem cell differentiation
P.011 | Joana Vilela (INSA)
Identification of disease risk variants in neurotransmission and synaptic genes in autism spectrum disorder
P.012 | Robertta Silva Martins (iMM, Faculdade de Medicina, Universidade de Lisboa)
Caffeine exposure regulated excitatory amino acids transmission in adolescent mice hippocampus
P.013 | Helena Vieira (CEDOC, Universidade NOVA de Lisboa)
Carbon monoxide modulation of cell metabolism and mitochondrial function during adult neurogenesis
P.014 | Liana Shvachiy (iMM, Faculdade de Medicina, Universidade de Lisboa)
Intermittent low-level lead exposure causes lifelong neuro and cardio impairments

SESSION II: Cellular and Molecular Neurosciences

P.015 | Cátia Rodrigues (CEDOC, Universidade NOVA de Lisboa)
RabGTPases as candidate mediators of SSR growth via RAL/exocyst complex
P.016 | Sara L. Paulo (iMM, Faculdade de Medicina, Universidade de Lisboa)
High caloric intake and aging: consequences for synaptic plasticity and rat behaviour performance
P.017 | Miguel Ribeiro (iMM, Faculdade de Medicina, Universidade de Lisboa)
Meningeal γδ T cell-derived IL-17 controls synaptic plasticity and cognitive behaviour
P.018 | André Furtado (CICS, Universidade da Beira Interior)
Age, genotype and sex affect the choroid plexus circadian clock in a mice model of Alzheimer’s disease
P.019 | Catarina Perdigão (CEDOC, Universidade NOVA de Lisboa)
Alzheimer’s Disease variants in the genetic risk factor bin1 increase beta-amyloid accumulation
P.020 | Farzaneh Sadat Mirfakhar (CEDOC, Universidade NOVA de Lisboa)
Impact of CD2AP a late-onset Alzheimer’s Disease risk factor on synapses
P.021 | Sílvia Sousa Chambel (Faculdade de Medicina, Universidade do Porto)
Sprouting of bladder afferents after spinal cord injury: the role of growth inhibitory proteins at the lumbosacral spinal cord
P.022 | Ana Cunha (Fundação Champalimaud)
Champalimaud molecular and transgenic tools platform
P.023 | Raquel Oliveira (Faculdade de Medicina, Universidade do Porto)
Botulinum toxin a in the treatment of bladder dysfunction after spinal cord injury: beyond SNAP 25 cleavage
P.024 | Hugo Vicente Miranda (CEDOC, Universidade NOVA de Lisboa)
Metformin prevents the deleterious effects of glycation in cellular models of Parkinson's disease
P.025 | Catarina M. Seabra (CNC, Universidade de Coimbra)
Protean - production and testing of human-derived neurons and brain organoids: advanced model probing in neurodevelopmental disorders
P.026 | Rebekab Koppenol (CBMR, Universidade do Algarve)
On the role of stress granules in autophagy
P.027 | Catarina Franco (Faculdade de Farmácia, Universidade de Lisboa) Withdrawn
P.028 | Maria Alexandra Brito (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Breast cancer brain metastasis: from bioinformatics analysis to biomarkers discovery in liquid biopsies and target identification in the brain parenchyma
P.029 | Sofia Galego (Faculdade de Farmácia, Universidade de Lisboa)
Brain metastasization of breast cancer: pathways and signaling
P.030 | Maria João Gama (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Unanswered role of cholesterol homeostasis in Parkinson’s Disease
P.031 | Gábor Orbán (Óbuda University, Hungary)
Towards simultaneous microelectrode array recordings and two-photon microscopy
P.032 | Pasqualino De Luca (CNC, Universidade de Coimbra)
BDNF increases synaptic expression of GluN2B-containing NMDAr in cultured hippocampal neuron
P.033 | Rafael S. Carvalho (CNC, Universidade de Coimbra)
Regulation of NMDA receptor surface dynamics by BDNF in cultured hippocampal neurons

SESSION III: Sensory Processing

P.034 | Ana Rita Costa (i3S, Universidade do Porto)
Chronic morphine enhances descending pain facilitation from the brain through a switch of μ-opioid receptor signaling
P.035 | Teresa Sousa (Universidade de Coimbra)
Studying the neuronal mechanisms underlying bistable perception: the role of adaptation, persistence, and inhibition on perceptual decision
P.036 | Raquel Pereira da Silva (i3S, Universidade do Porto)
The descending noradrenergic spinal modulation is impaired during prolonged joint inflammatory pain conditions
P.037 | Marília Sousa (Faculdade de Medicina, Universidade do Porto)
Mu-opioid receptor signalling switch to excitatory following chronic morphine persists upon treatment cessation
P.038 | Mikhail S. Nikitenko (The Federal Research Center of Coal and Coal Chemistry SB RAS, Russia)
Basics of creating a mobile operator position concept by using brain-computer interface
P.039 | Inês Laranjeira (ICVS, Universidade do Minho)
Pain severity is associated with the development of depression and anxiety in patients with osteoarthritis: systematic review and meta-analysis
P.040 | Diana Rodrigues (ICVS, Universidade do Minho)
Nociceptive, emotional and electrophysiological characterization of the chronic constriction injury model of experimental traumatic neuropathic pain in female Wistar Han rats

SESSION IV: Rare Disorders

P.041 | Carina Maranga (IST, Universidade de Lisboa)
Disease modeling of Angelman Syndrome using hIPSC-derived cerebellar organoids
P.042 | Ana Moreira de Sá (CNC, Universidade de Coimbra)
Blockade of adenosine A2A receptors improves motor learning and grip strength in an Angelman Syndrome mouse model
P.043 | Fernanda Murtinheira (ITQB, Universidade NOVA de Lisboa)
Towards a smaller but functional sacsin protein for arsacs gene therapy
P.044 | Liliana Mendonça (CNC, Universidade de Coimbra)
Cyp46A1- gene therapy alleviates Machado-Joseph Disease
P.045 | Ana Vasconcelos-Ferreira (CNC, Universidade de Coimbra)
Reinstating levels of dysregulated autophagy-associated transcripts alleviates europathology and motor impairments of mouse models of Machado-Joseph Disease

SESSION V: Neural Circuits

P.046 | Haissa de Castro Abrantes (University of Lausanne, Switzerland)
The lactate receptor HCAR1 modulates neuronal network activity through the activation of Gαi and Gβɣ subunits
P.047 | Madalena Esteves (ICVS, Universidade do Minho)
Prefrontal-striatal functional encoding of impulsivity – a brief (3 seconds) history of brain time
P.048 | Vanessa Lourenço (CNC, Universidade de Coimbra)
Adenosine A2A receptors in the basolateral amygdala modulate fear extinction
P.049 | Cátia D. F. Lopes (INEB, i3S, Universidade do Porto)
Studying axonal signal propagation dynamics on a platform combining microelectrodes and microfluidics
P.050 | Miguel Aroso (INEB, Universidade do Porto)
A new computational tool for analysing neuronal activity from voltage and calcium imaging
P.051 | João Morais (Faculdade de Medicina, Universidade do Porto)
Behavioral effects of DRN stimulation on a head-fixed foraging task

SESSION VI: Glia / Neuroinflammation

P.052 | Ricardo Quiteres (ITQB, Universidade NOVA de Lisboa)
Visualization of astrogliogenic signaling by super-resolution microscopy
P.053 | Diogo Carregosa (CEDOC, Universidade NOVA de Lisboa)
Building the bridge between small phenolic conjugates, neuroinflammation and neurodegenerative diseases
P.054 | Joana Gomes (iMM, Faculdade de Medicina, Universidade de Lisboa)
Astrocytic signaling upon Aβ-mediated excitotoxicity
P.055 | Joana Gonçalves-Ribeiro (iMM, Faculdade de Medicina, Universidade de Lisboa)
Astrocytic CB1R enhances glast activity in a Ca2+ dependent manner
P.056 | Antónia Fortunato (iMM, Faculdade de Medicina, Universidade de Lisboa)
NLRP3 inflammasome assembly in microglia-induced reactive astrocytes
P.057 | Margarida G. Godinho (iMM, Faculdade de Medicina, Universidade de Lisboa)
ROS-mediated NLRP3 activation in a model of epileptogenesis in organotypic slices
P.058 | Ana G. Mestre (IT, IST, Universidade de Lisboa)
Electrophysiological activity of a population of astrocytes
P.059 | Diana Nascimento (ICVS, Universidade do Minho)
Minisog: temporal and spatial control over astrocyte exocytosis
P.060 | João Oliveira (ICVS, Universidade do Minho)
The role of astrocytic calcium signaling in development and aging
P.061 | Adelaide Fernandes (Faculdade de Farmácia, Universidade de Lisboa)
A1 polarized IPSCs-derived astrocytes with the PSEN1Eδ9 mutation show deregulated inflammatory dynamics
P.062 | Gonçalo Garcia (iMed.ULisboa, Faculdade de Farmácia, Universidade de Lisboa)
Manipulation of miR-124 expression on neuronal APP-SWE cells results in different microglial polarization through paracrine signaling
P.063 | José F. Cascalheira (CICS, Universidade da Beira Interior)
The inhibitory effect of adenosine on human astrocyte proliferation is absent in glioblastoma cell lines
P.064 | Ricardo Letra-Vilela (ITQB; Universidade NOVA de Lisboa)
Effect of post-translational modifications on the behavior, function and fate of stimulated STAT3 homo- and heterodimers
P.065 | Ivan L. Salazar (CNC, Universidade de Coimbra)
Novel cerebrospinal fluid biomarkers of multiple sclerosis

SESSION VII: Psychiatric Disorders / Addiction

P.066 | Eduar Herrera Murcia (Universidade Icesi, Colombia)
Social cognition: moral and theory of the mind in institutionalized adolescents and vulnerability condition
P.067 | Renata L. Alves (i3S, Universidade do Porto)
Maternal separation on mothers with different susceptibility to depression: impact on cognitive adolescent offspring behaviour
P.068 | Nuno M. C. Da Costa (ICVS, Universidade do Minho)
Does priming subjects, with not only resting state but also with mindfulness or/and guided imagery, affect self-regulation of smr neurofeedback? Framework to improve brain self-regulation and support the rehabilitation of disorders such as depression, anxiety, stress and attention control
P.069 | Sara R. Tanqueiro (iMM, Faculdade de Medicina, Universidade de Lisboa)
Does BDNF loss of function in the prefrontal cortex underlie cognitive deficits in the subchronic phencyclidine model of schizophrenia?
P.070 | Pedro A. Pereira (DBM, Faculdade de Medicina, Universidade do Porto)
Effects of chronic alcohol consumption and withdrawal on the cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei of the rat: an unbiased stereological study
P.071 | Cátia Santa (CNC, Universidade de Coimbra)
Analysis of the quantitative proteomic signature in PBMCS of first-episode psychosis patients

SESSION VIII: Neurodegeneration / Physiological Aging Brain

P.072 | Beatriz Vila-Verde (BioISI, Universidade de Lisboa)
Impaired response to novelty and motor behaviour in the d-Gal rat model of accelerated aging
P.073 | Catarina Ferreira (iMM, Faculdade de Medicina, Universidade de Lisboa)
SEPT5 phosphorylation status as modulator of synaptic function in the hippocampus
P.074 | Cláudia Serre-Miranda (ICVS, Universidade do Minho)
Peripheral inflammatory mediators and distinct cognitive profiles in healthy aging
P.075 | Dina Pereira (CNC, Universidade de Coimbra)
The role of ageing in polyglutamine-induced neurodegeneration: a study in Machado-Joseph disease models
P.076 | Sandra I. Anjo (CNC, Universidade de Coimbra)
PBMCS as a potential source of biomarkers in neurodegenerative diseases – preliminary study
P.077 | Rui J. Nobre (CNC, Universidade de Coimbra)
Non-invasive and allele-specific silencing therapy for polyglutamine disorders: the case of Machado-Joseph disease/spinocerebellar ataxia type 3
P.078 | Ildete L. Ferreira (CNC, Universidade de Coimbra)
Postsynaptic decrease of SAPAP3 scaffold protein in Huntington’s disease
P.079 | André Miguel Miranda (ICVS, Universidade do Minho)
Neuronal endolysosomal dysfunction and exosome secretion: differential impact of PI3P and PI(3,5)P2 deficiency
P.080 | Daniela Marinho (CNC, Universidade de Coimbra)
Role of class I histone deacetylase inhibitors in cell and animal models of Alzheimer’s disease
P.081 | João Vaz-Silva (ICVS, Universidade do Minho)
Identification of RAB35 as a negative regulator of Aβ production
P.082 | Maria José Diógenes (iMM, Faculdade de Medicina, Universidade de Lisboa)
Analysis of the transcriptomic response induced by the intracellular domain (TrkB-ICD) of TrkB receptor in rat cortical neurons
P.083 | Rita F. Belo (iMM, Faculdade de Medicina, Universidade de Lisboa)
The neuroprotective effect of amidated-kyotorphin on Alzheimer’s disease